People who have a condition called phenylketonuria (PKU) should avoid using aspartame. PKU is a rare genetic disorder in which the body cannot break down an amino acid called phenylalanine properly. Aspartame contains phenylalanine, so when people with PKU consume aspartame, the levels of phenylalanine in their bodies can become dangerously high.
Phenylalanine is found in many foods, but people with PKU must follow a strict diet low in phenylalanine to prevent the buildup of toxic levels in their bodies. Aspartame, which is commonly used as an artificial sweetener in many foods and beverages, can significantly increase the phenylalanine intake for individuals with PKU.
The reason why high levels of phenylalanine are toxic for people with PKU is because their bodies lack an enzyme called phenylalanine hydroxylase, which is responsible for breaking down phenylalanine. As a result, phenylalanine accumulates in the bloodstream and can lead to intellectual disability, developmental delays, and other neurological problems if not properly managed.
It is important for individuals with PKU to carefully read food and beverage labels to identify if aspartame is present. The Food and Drug Administration (FDA) requires products containing aspartame to include a warning label stating “Phenylketonurics: Contains Phenylalanine” to alert individuals with PKU about its presence.
If you or someone you know has PKU, it is crucial to consult with a healthcare professional or a registered dietitian who specializes in metabolic disorders to develop a suitable diet plan. This plan will focus on restricting phenylalanine intake and finding alternative sweeteners that do not contain aspartame.
Individuals with phenylketonuria (PKU) should avoid using aspartame due to its high phenylalanine content. PKU is a rare genetic disorder that impairs the body’s ability to break down phenylalanine properly, leading to potentially toxic levels in the bloodstream. It is essential for people with PKU to follow a strict low-phenylalanine diet and consult with healthcare professionals to manage their condition effectively.