What happens if you take too much choline?

Answered by Tom Adger

Taking too much choline can have several negative effects on the body. One of the most common symptoms of excessive choline intake is a fishy body odor. This odor is caused by trimethylamine, a compound that is produced when choline is broken down in the body. While this odor is generally harmless, it can be quite unpleasant and embarrassing for individuals experiencing it.

In addition to the fishy body odor, excessive choline intake can also lead to gastrointestinal issues such as vomiting and diarrhea. These symptoms can be quite uncomfortable and disruptive to daily life. It is important to note that the severity of these symptoms may vary from person to person, and some individuals may be more sensitive to high levels of choline than others.

Another potential side effect of excessive choline intake is excessive sweating and salivation. This can be particularly bothersome and may cause discomfort and social embarrassment. It is important to stay hydrated and maintain electrolyte balance if experiencing excessive sweating due to choline intake.

Moreover, taking too much choline can also result in low blood pressure, also known as hypotension. This can cause symptoms such as dizziness, lightheadedness, and fainting. It is important to monitor blood pressure levels regularly and seek medical attention if experiencing persistent low blood pressure.

One of the more serious potential risks of excessive choline intake is liver damage. Although rare, high levels of choline can lead to an accumulation of fats in the liver, resulting in conditions such as fatty liver disease. Individuals with pre-existing liver conditions or those who consume excessive amounts of alcohol may be particularly susceptible to liver damage caused by choline.

Furthermore, research has suggested that high amounts of choline may increase the risk of heart disease. Although the exact mechanism is not fully understood, it is believed that excessive choline intake can lead to the production of a compound called trimethylamine N-oxide (TMAO), which has been associated with an increased risk of cardiovascular problems. However, it is important to note that more research is needed to fully understand the relationship between choline and heart disease.

While choline is an essential nutrient for the body, excessive intake can lead to various negative effects. These can include a fishy body odor, gastrointestinal issues, excessive sweating and salivation, low blood pressure, and liver damage. Additionally, high amounts of choline may potentially increase the risk of heart disease. It is important to maintain a balanced and moderate intake of choline to avoid these potential risks and consult with a healthcare professional if any symptoms or concerns arise.